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To ensure that it remains in step with public needs, this RFI invites stakeholders throughout the scientific research, advocacy, and can you buy viagra over the counter clinical practice communities, as well as the general public to comment on the NIH-Wide Strategic Plan for erectile dysfunction treatment Research. Organizations are strongly encouraged to submit a single response that reflects the views of their organization and their membership as a whole. This RFI is open for public comment for a period of five weeks.

Comments must be received by can you buy viagra over the counter 11:59:59 p.m. (ET) on December 7, 2020 to ensure consideration. Start Printed Page 69336 All comments must be submitted electronically on the submission website, available at.

Https://rfi.grants.nih.gov/​?. S=​5f91a3efdb70000018003362. Start Further Info Please direct all inquiries to.

Beth Walsh, nihstrategicplan@od.nih.gov, 301-496-4000. End Further Info End Preamble Start Supplemental Information Urgent public health measures are needed to control the spread of the novel erectile dysfunction (erectile dysfunction) and the disease it causes, erectile dysfunction disease 2019, or erectile dysfunction treatment. Scientific research to improve basic understanding of erectile dysfunction and erectile dysfunction treatment, and to develop the necessary tools and approaches to better prevent, diagnose, and treat this disease is of paramount importance.

The NIH-Wide Strategic Plan for erectile dysfunction treatment Research (available at. Https://www.nih.gov/​research-training/​medical-research-initiatives/​nih-wide-strategic-plan-erectile dysfunction treatment-research), released on July 13, 2020, provides a framework for achieving this goal. It describes how NIH is rapidly mobilizing diverse stakeholders, including the biomedical research community, industry, and philanthropic organizations, through new programs and existing resources, to lead a swift, coordinated research response to this global viagra.

The plan outlines how NIH is implementing five Priorities, guided by three Crosscutting Strategies. Priorities Priority 1. Improve Fundamental Knowledge of erectile dysfunction and erectile dysfunction treatment ○ Objective 1.1.

Advance fundamental research for erectile dysfunction and erectile dysfunction treatment ○ Objective 1.2. Support research to develop preclinical models of erectile dysfunction and erectile dysfunction treatment ○ Objective 1.3. Advance the understanding of erectile dysfunction transmission and erectile dysfunction treatment dynamics at the population level ○ Objective 1.4.

Understand erectile dysfunction treatment disease progression, recovery, and psychosocial and behavioral health consequences Priority 2. Advance Detection and Diagnosis of erectile dysfunction treatment ○ Objective 2.1. Support research to develop and validate new diagnostic technologies ○ Objective 2.2.

Retool existing diagnostics for detection of erectile dysfunction ○ Objective 2.3. Support research to develop and validate serological assays Priority 3. Advance the Treatment of erectile dysfunction treatment ○ Objective 3.1.

Identify and develop new or repurposed treatments for erectile dysfunction ○ Objective 3.2. Evaluate new, repurposed, or existing treatments and treatment strategies for erectile dysfunction treatment ○ Objective 3.3. Investigate strategies for access to and implementation of erectile dysfunction treatments Priority 4.

Improve Prevention of erectile dysfunction ○ Objective 4.1. Develop novel treatments for the prevention of erectile dysfunction treatment ○ Objective 4.2. Develop and study other methods to prevent erectile dysfunction transmission ○ Objective 4.3.

Develop effective implementation models for preventive measures Priority 5. Prevent and Redress Poor erectile dysfunction treatment Outcomes in Health Disparity and Vulnerable Populations ○ Objective 5.1. Understand and address erectile dysfunction treatment as it relates to health disparities and erectile dysfunction treatment—vulnerable populations in the United States ○ Objective 5.2.

Understand and address erectile dysfunction treatment maternal health and pregnancy outcomes ○ Objective 5.3. Understand and address age-specific factors in erectile dysfunction treatment ○ Objective 5.4. Address global health research needs from erectile dysfunction treatment Crosscutting Strategies Partnering to promote collaborative science ○ Leverage existing NIH-funded global research networks and private sector, public, and non-profit relationships ○ Coordinate with Federal partners ○ Establish new public-private partnerships Supporting the research workforce and infrastructure ○ Conduct research to elucidate how erectile dysfunction treatment impacts the scientific workforce ○ Provide research resources ○ Leverage intramural infrastructure to support extramural researchers ○ Conduct virtual peer review processes Investing in data science ○ Create new data science resources and analytical tools ○ Develop shared metrics and terminologies NIH seeks comments on any or all of, but not limited to, the following topics.

Significant research gaps or barriers not identified in the existing framework above. Resources required or lacking or existing leverageable resources (e.g., existing partnerships, collaborations, or infrastructure) that could advance the strategic priorities. Emerging scientific advances or techniques in basic, diagnostic, therapeutic, or treatment research that may accelerate the research priorities detailed in the framework above.

And Additional ideas for bold, innovative research initiatives, processes, or data-driven approaches that could advance the response to erectile dysfunction treatment. NIH encourages organizations (e.g., patient advocacy groups, professional organizations) to submit a single response reflective of the views of the organization or membership as a whole. Responses to this RFI are voluntary and may be submitted anonymously.

Please do not include any personally identifiable information or any information that you do not wish to make public. Proprietary, classified, confidential, or sensitive information should not be included in your response. The Government will use the information submitted in response to this RFI at its discretion.

The Government reserves the right to use any submitted information on public websites, in reports, in summaries of the state of the science, in any possible resultant solicitation(s), grant(s), or cooperative agreement(s), or in the development of future funding opportunity announcements. This RFI is for informational and planning purposes only and is not a solicitation for applications or an obligation on the part of the Government to provide support for any ideas identified in response to it. Please note that the Government will not pay for the preparation of any information submitted or for use of that information.

We look forward to your input and hope that you will share this RFI opportunity with your colleagues. Start Signature Dated. October 27, 2020.

Lawrence A. Tabak, Principal Deputy Director, National Institutes of Health. End Signature End Supplemental Information [FR Doc.

2020-24202 Filed 10-30-20. 8:45 am]BILLING CODE 4140-01-PSign up for our newsletter Explore full page map The language we’ve heard to describe erectile dysfunction treatment in rural America is evolving. Early in the viagra, healthcare professionals were concerned.

Later, some were alarmed. Now, what I hear sounds a lot like shock. In a story we published earlier today, Alan Morgan with the National Rural Health Association called the rural viagra a horror story.

Carrie Henning-Smith with the University of Minnesota Rural Health Research Center has another word. Ominous. That’s not the kind of comforting word we like to hear from our caregivers.

But a cheerful bedside manner doesn’t seem to be doing the job with rural America. €œI think that there was a chance early on to try to contain this, when we had this as a mostly urban phenomenon back in March and April,” said Henning-Smith, who is also an associate professor in the School of Public Health at the University of Minnesota. €œWe blew way past that.

And now this has spread into virtually every county in the country, in metro and non-metro alike.” Welcome to the rural wave – the phase of the viagra that is swamping rural America with record numbers of erectile dysfunction treatment s. Late this spring, we still had swaths of rural America – mostly in the Midwest and Great Plains – that went weeks without a single case. On June 1, nearly 9% of rural counties hadn’t reported any s.

Today, only one county in the Lower 48 hasn’t reported a case of erectile dysfunction treatment. For the rest of rural America, most of the news is bad. The rate of new s in rural counties is 65% higher than in urban counties.

The number of new cases in rural America has set a record each of the last five weeks. Seventy percent of rural counties are at risk of uncontrolled spread, what the White House erectile dysfunction Task Force calls the red zone. Something different is happening in rural America in this surge.

The coastal and urban regions that bore the brunt of the summer surge look relatively contained now. The trouble spots, as shown in the map above, are in the interior. Why is erectile dysfunction treatment surging now in these areas that got off relatively easy this summer?.

Henning-Smith, who holds three master’s level degrees and a PhD, cited several possibilities. The first may be “erectile dysfunction treatment fatigue.” “It took longer to get to rural areas and it’s hard to keep the public relentlessly engaged and being mindful and cautious as the viagra wears on,” she said. Another factor is politics, she said.

€œThere are definitely some strong relationships where we’re seeing very, very mixed messaging at the highest levels of the federal government about even the most basic precautions for erectile dysfunction treatment.” And some of it is just the nature of the erectile dysfunction. All things equal, the viagra spreads from one host to the next. Think of spreading peanut butter on toast.

You won’t get it to a uniform thickness, but each swipe of the knife gets you closer. €œ[The graphs] give every indication that rural areas will catch up to urban, and we’ll see proportional rates of erectile dysfunction treatment cases and erectile dysfunction treatment deaths in rural, relative to urban,” Henning-Smith said. Rural areas could even get worse than urban ones eventually, she said.

A host of factors make that a possibility. Rural employment may not be as suited for remote work. Services like online grocery ordering and delivery are less available in rural areas.

Lack of broadband may mean rural people have to do more activities in person. Contact tracing may not be as robust. Testing can be more challenging in less densely populated areas.

Henning-Smith, whose research focuses on health equity, also said race is a factor in how erectile dysfunction treatment is spreading and what happens when it reaches a community. €œI don’t think we’re talking enough about the intersection of [race and rurality], of the impact of structural racism among rural residents,” she said. Most people have a choice about whether to wear a mask.

Fewer of us have a choice about other factors that contribute to the spread of erectile dysfunction treatment. €œWho has the luxury of containing themselves to their household so they don’t get it?. € she said.

€œWho lives in a house that’s not crowded, so they’re not spreading it to their family members?. Who has access to healthcare, decent health insurance?. Who still has a hospital or a clinic in town to get the care that they need, if they need it?.

€ Tim Murphy contributed data analysis to this article. Before You Go The Daily Yonder is a nonprofit news platform dedicated to reporting on rural people, places, and issues. Donations from readers like you makes it possible for us to fulfill this important mission.

So far this year, we’ve helped readers understand where rural America fits in the erectile dysfunction treatment viagra, the 2020 election, and the fight for racial equity. For the rest of 2020, you have a special opportunity to double your contribution to the Daily Yonder. Your gift will be matched dollar for dollar by NewsMatch, a nonprofit news funding program.

All you have to do to help us get this extra support is make a gift, in any amount.

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New research can you buy viagra over the counter shows that deaths due to the mix of substance abuse and suicides known as “diseases of despair” declined slightly in 2018. But the mortality rates can you buy viagra over the counter throughout the Ohio Valley and Appalachian region are still higher than the national average. A report from the Appalachian Regional Commission found that overall mortality rates from diseases of despair, which include suicide, liver disease, and overdoses, decreased between 2017 and 2018 — the first decline since 2012. But the research, done by the Walsh can you buy viagra over the counter Center for Rural Health Analysis and Center for Rural Health Research at East Tennessee State University, shows those mortality rates are still disproportionately higher for Appalachia compared to the rest of the United States. €œWhat’s interesting about this is how you define the decline,” Michael Meit explained.

Meit is the director can you buy viagra over the counter of research and programs at the Center for Rural Health Research at ETSU and an author of the report. He said that the region’s diseases of despair mortality rate only decreased by one percentage point. €œIn 2015, diseases of despair as a group was 37% higher in the Appalachian region compared to the rest of the nation and now 2018 data shows it’s 36% higher.” By using the Centers for Disease Control and Prevention mortality rates, researchers are able to keep track of what’s can you buy viagra over the counter happening in the region. 2018 is the most recent data on record. What Meit found most can you buy viagra over the counter interesting is the profile shift of the types of deaths within the region.

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The reports notes that “the impact of erectile dysfunction treatment will likely lead to an increase in mortality from disease of despair, particularly as the Appalachian region and the rest of the United States experience economic can you buy viagra over the counter challenges as a result of the viagra, isolation, and limitations on access to in-person treatment and recovery support.” Meit said anecdotal evidence suggests that there could be an increase in overdose deaths in 2020. That data won’t be available until late 2021 or 2022.CUBA, N.M. (AP) — The midday arrival of a school bus at Cyliss Castillo’s home on the remote edge of a mesa breaks up the long days of boredom and isolation for the high school senior.The driver hands over food in white plastic bags, collects Castillo’s school assignments and offers some welcome conversation before setting out for another home.The closing of classrooms and the switch to remote learning because of the erectile dysfunction have left Castillo and other students in this school district on the sparsely can you buy viagra over the counter populated fringe of the Navajo Nation in New Mexico profoundly isolated — cut off from direct human contact and, in many cases, unconnected to the grid.ADVERTISEMENTLike many of his neighbors, Castillo does not have electricity, let alone internet.It is yet another way in which the viagra has exposed the gap between the haves and have-nots in the U.S.“There’s not a lot to do here. You clean up, pick up trash or build stuff. Like, I built that shed right there,” the 18-year-old Castillo said, pointing at a pitched-roof plywood shed.“Hopefully, hopefully by next can you buy viagra over the counter semester we’ll be going back into school,” he said.

€œI don’t like online. I like to be, you know, in school, learning can you buy viagra over the counter. That’s just not me. I just find it a lot easier and a lot better than just out here, not doing nothing.”The Cuba Independent School District, centered in a village of 800 people, has kept the buses running as a way to bring school to students who live in widely separated cabins, trailers, campers can you buy viagra over the counter and other structures on a vast checkboard of tribal, federal and county land. On their routes, the buses carry school assignments, art supplies, meals and counselors who check in with students who are struggling with online bullying, abuse, thoughts of suicide or other problems.The buses are a lifeline for families in the Cuba school district, of whom nearly half are Hispanic and half are Native American, including many Navajo-speaking English-language learners.

Many do not have running water can you buy viagra over the counter. Castillo and others with no electricity charge their school-issued laptops with car batteries or at a relative’s house. One student has sent her laptop on the buses to be charged can you buy viagra over the counter at school. This far out, internet service is unavailable or prohibitively expensive.For students without home internet, the buses bring USB drives loaded with assignments and video lessons from teachers. Some students like Castillo eventually asked for paper packets because of the can you buy viagra over the counter difficulty in charging laptops.ADVERTISEMENTWith erectile dysfunction treatment cases spiking in New Mexico to their highest levels yet, it is unclear when the district will begin offering in-person classes again.The district has a record of adapting to challenges, and a high school graduation rate of 83% — well above the state average — to show for it.

It has long employed a “community school” approach in which social workers, nurses and teachers help students around the clock, not just during the school day, on the theory that they will do better academically if their home life can be made better.All students were issued Chromebooks in 2019, well before the erectile dysfunction outbreak. That made the shift to distance learning easier in March can you buy viagra over the counter when school buildings shut down. Other rural districts around the country have likewise been engineering ways to connect with students who are otherwise disengaged during the viagra. In San Joaquin, California, about 30 miles (48 kilometers) west of Fresno, the Golden Plains Unified School District found early in the viagra that students were out can you buy viagra over the counter working rather than doing schoolwork. €œWe would have kids call from the fields.

They were picking peaches,” said Andre Pecina, can you buy viagra over the counter an assistant superintendent, who noted only 40% of high school students were participating in distance learning. €œOnce erectile dysfunction treatment happened, parents were like, `Let’s go to work.’”To bring students back into the fold, the district reached out to parents by phone to set teacher conferences early in the school year and ordered hundreds of internet hot spots. It is also delivering school materials and electronic devices to students.In New Mexico, before the buses set out from Cuba High School each day, about 25 cafeteria workers, bus drivers and other staff spend over an hour loading them with milk, produce, prepared meals, toilet paper and other necessities for can you buy viagra over the counter the families.On board one day in late October was head district counselor Victoria Dominguez, who was checking on two students who had suicidal thoughts. She was bringing one a pair of skateboard shoes. In the spring, a screening system for messages sent by students flagged one or two a week as showing signs can you buy viagra over the counter of possible emotional trouble.

Now she is seeing dozens in single week. €œI’m worried for the winter can you buy viagra over the counter months. It’s going to get darker. It’s going to get colder and you can’t go can you buy viagra over the counter outside,” Dominguez said. As erectile dysfunction treatment rates spiked, the school switched to making bus deliveries every other day, instead of every day.“They’ll still get the same amount of food, but they won’t get the same amount of human contact,” she said.Along the bus route, a home is situated every few miles.

The Castillos built their cabin from scratch and use a small camper as well.The road from the high school turned from asphalt to gravel can you buy viagra over the counter to deeply rutted dirt. The oak and pine trees gave way to sagebrush and gaunt junipers before the bus came to halt in front of a cluster of houses.Students poured out to greet the bus driver, Kelly Maestas. He asked them how they were doing and handed out lunches can you buy viagra over the counter. Dominguez went to shoot baskets with some of the older kids.Among them was 15-year-old Autumn Wilson, a shy sophomore whose father died after she started high school last year. Then school can you buy viagra over the counter shut down.

Now she can’t play on the volleyball team anymore. Dominguez connected can you buy viagra over the counter her with a therapist on an earlier visit. Autumn said the sadness over the loss makes it difficult for her to finish schoolwork. But she can you buy viagra over the counter finds joy riding horses when her grandfather takes her to the family corral. And she looks forward to the visits from Maestas, who brought her candy for her birthday.

€œKelly, he’s really funny to talk to can you buy viagra over the counter. And if you’re feeling sad you can really talk to him,” she said, “and you can trust him.”___Associated Press writer Jeff Amy in Atlanta contributed to this report.___Attanasio is a corps member for the Associated Press/Report for America Statehouse News Initiative. Report for America is a nonprofit national service program that places can you buy viagra over the counter journalists in local newsrooms to report on under-covered issues. Follow Attanasio on Twitter..

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Brown and Shyy from the US focus on Soft tissue s, Abscesses, Pyomyositis and Necrotizing Fasciitis, there is much to be learnt here.Germini et al have reported their findings of the quality of abstracts of randomised controlled trials (RCTs) in 10 emergency medicine journals.1 They studied two periods (2005–2007 and 2014–2015), before and after the publication of the Consolidated Standards of Reporting Trials (CONSORT) statement extension for abstracts (CONSORT-EA). They found that the overall quality of abstracts reported in emergency medicine journals was low in both periods, with only slight and non-statistically significant improvement in the total number of correctly reported items after the publication of the CONSORT-EA guidelines.The CONSORT statement, for those who are not primarily researchers, was developed in 1996 and was the first of what are now hundreds of guidelines for how to report the methods, results and implications of research. The idea behind these guidelines is to promote complete transparency in how studies are conducted, and to alert readers to potential sources viagra pills amazon of bias (systematic error) in how the study was conceived or conducted. They usually take the form of a checklist and are designed for the type of research being reported.

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HeadlinesEvery year can you buy viagra over the counter approximately 1.4 million people attend the viagra for women price ED in the UK with a head injury. The National Institute for Health and Care Excellence (NICE) recommends routine CT imaging of all patients with mild head injury taking anticoagulants within 8 hours of injury. The risk of adverse outcomes following mild head injury when taking a DOAC is uncertain, nonetheless to many of us it often feels like an unnecessary investigation and can you buy viagra over the counter over exposure of a patient who is clinically well and without symptoms. So you may be interested to read a paper by Fuller and colleagues from Sheffield, who conducted an observational cohort study with the aim of estimating the risk of adverse outcome after mild head injury in patients taking DOACs to guide emergency department management. The primary endpoint was adverse outcome within 30 days, comprising.

Neurosurgery, ICH, or death due to can you buy viagra over the counter head injury. They found the risk of adverse outcomes following mild head injury in patients taking DOACs appears low. The authors suggest these findings would support shared patient-clinician decision making, rather than routine imaging following minor head injury while taking DOACs. This might be music to your ears and indeed the radiologist, especially in the middle of the night.Head homeChildren are no exception where head injuries are concerned, it is estimated that more than 700 000 of them in the UK attend can you buy viagra over the counter hospital every year with a head injury and less than 1% of these need neurosurgical intervention. Aldridge and his colleagues hypothesised that a proportion of these children could be screened and discharged at triage with appropriate safety netting by a nurse using a clinical decision tool.

They prospectively screened all children (n1739) at triage over a 6 month period in 2018 using a mandated electronic ‘Head Injury Discharge at Triage ‘questionnaire (HIDATq).Their findings suggest a negative HIDATq appears safe for their department and that potentially 20% of all children presenting with head injuries could have been discharged by nurses using the screening tool. This figure increases can you buy viagra over the counter to 50% if children with lacerations or abrasions were given advice and discharged at triage. They do point out however that a multi- centre study is required to validate the tool. Arguably any intervention that can safely minimise length of stay for children in the ED is worthy of consideration and will appeal to children and their carers.Affairs of the heartChest pain continues to be a common presentation in the ED but medical advances and technology have changed and expedited the way we assess and manage these patients. Are we seeing more or less patients presenting can you buy viagra over the counter with chest pain?.

Aalam and colleagues in the US undertook a retrospective descriptive study of trends in utilisation and care of ED chest pain visits from (2006 to 16) using data from the Healthcare Cost and Utilisation Project (HCUP) database, a national sample of US ED visits and hospitalizations. In their study, can you buy viagra over the counter they describe demographic, care, and cost trends for chest pain over 11 years. Unsurprisingly, they found ED visits for patients with chest pain increased but inpatient admission rate declined from 19% in 2006 to 3.9% in 2016. Is this due to same day cardiac CTA and shorter Troponin testing times?. I’ll leave you to work can you buy viagra over the counter this one out when you have read this paper.Troponin or not?.

Patients who present with chest pain often face lengthy delays in the ED to rule out ACS even though less than 10% are diagnosed with ACS. Previous studies have shown that up to 46% of cardiac troponin (cTn) testing in the ED is deemed inappropriate and results in not just wasted costs but unnecessary procedures. Moreover, it can also cause alarm can you buy viagra over the counter http://h2owireless.de/ueber-uns/ and anxiety without adding value. Smith and colleagues in the US hypothesised that this low risk patient population does not benefit from testing and could be safely discharged following an ECG. They conducted a secondary analysis of the HEART Pathway Implementation Study.

HEART Pathway risk assessments (HEAR scores and serial troponin testing at 0 and can you buy viagra over the counter 3 hours) were completed by providers on adult patients with chest pain from three US sites. Major adverse cardiac events (MACE) (composite of death, myocardial infarction (MI) and coronary revascularisation) at 30 days was determined. Their findings suggest that patients with HEAR scores of 0 and 1 represent a very-low risk group that may not require troponin testing to achieve a missed MACE rate. So maybe can you buy viagra over the counter less delays in future?. The ED on your doorstepShielding our frail older patients has been an ongoing challenge in this erectile dysfunction treatment viagra, one hospital has bucked the trend and taken the ED to the patient.

McNamara and colleagues in Dublin describe can you buy viagra over the counter how a bespoke weekend service assessing older people who fell at home was expanded to meet the evolving needs of shielding older people in the viagra. The team consisted of an advanced paramedic, an ED registrar and an occupational therapist in conjunction with local consultants in geriatric an emergency medicine. All three professionals travelled and attended calls together covering a wide catchment both urban and rural. The service carried with them OT equipment and had access to near patient can you buy viagra over the counter testing and point of care ultrasound. Patients were registered to the ED by phone.

They attended 592 patients in the first 105 days of operation 43 of whom were transferred to hospital, 41 being admitted. They also undertook 21 can you buy viagra over the counter additional visits to care homes to give advice and control support. Do read this paper there is a lot of detail about set up and costs as well as examples of cases seen. It sounds like the quality care you would wish for your older relatives. It may be one of the silver linings of the viagra and a viable pragmatic model for the future.Sono case seriesDon’t forget to have a can you buy viagra over the counter read of our Sono Case series.

Brown and Shyy from the US focus on Soft tissue s, Abscesses, Pyomyositis and Necrotizing Fasciitis, there is much to be learnt here.Germini et al have reported their findings of the quality of abstracts of randomised controlled trials (RCTs) in 10 emergency medicine journals.1 They studied two periods (2005–2007 and 2014–2015), before and after the publication of the Consolidated Standards of Reporting Trials (CONSORT) statement extension for abstracts (CONSORT-EA). They found that the overall quality of abstracts reported in emergency medicine journals was low in both periods, with only slight and non-statistically significant improvement in the total number of correctly reported items after the publication of the CONSORT-EA guidelines.The CONSORT statement, for those who are not primarily researchers, was developed in 1996 and was the first of what are now hundreds of guidelines for how to report the methods, results and implications of research. The idea behind these can you buy viagra over the counter guidelines is to promote complete transparency in how studies are conducted, and to alert readers to potential sources of bias (systematic error) in how the study was conceived or conducted. They usually take the form of a checklist and are designed for the type of research being reported. In addition to CONSORT for RCTs, the most commonly used checklists in the emergency medicine literature are those for observational studies (Strengthening the Reporting of Observational Studies in Epidemiology (STROBE)), diagnostic studies (Standards for Reporting of Diagnostic Accuracy Studies (STARD)), systematic reviews (PRISMA:Preferred ….